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Spark Therapeutics: Pioneering Gene Therapy SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

Case Study SWOT Analysis Solution

Case Study Description of Spark Therapeutics: Pioneering Gene Therapy


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Authors :: Robert F. Higgins

Topics :: Innovation & Entrepreneurship

Tags :: , SWOT Analysis, SWOT Matrix, TOWS, Weighted SWOT Analysis

Swot Analysis of "Spark Therapeutics: Pioneering Gene Therapy" written by Robert F. Higgins includes – strengths weakness that are internal strategic factors of the organization, and opportunities and threats that Gene Therapeutics facing as an external strategic factors. Some of the topics covered in Spark Therapeutics: Pioneering Gene Therapy case study are - Strategic Management Strategies, and Innovation & Entrepreneurship.


Some of the macro environment factors that can be used to understand the Spark Therapeutics: Pioneering Gene Therapy casestudy better are - – increasing household debt because of falling income levels, banking and financial system is disrupted by Bitcoin and other crypto currencies, wage bills are increasing, competitive advantages are harder to sustain because of technology dispersion, digital marketing is dominated by two big players Facebook and Google, challanges to central banks by blockchain based private currencies, increasing inequality as vast percentage of new income is going to the top 1%, technology disruption, customer relationship management is fast transforming because of increasing concerns over data privacy, etc



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Introduction to SWOT Analysis of Spark Therapeutics: Pioneering Gene Therapy


SWOT stands for an organization’s Strengths, Weaknesses, Opportunities and Threats . At Oak Spring University , we believe that protagonist in Spark Therapeutics: Pioneering Gene Therapy case study can use SWOT analysis as a strategic management tool to assess the current internal strengths and weaknesses of the Gene Therapeutics, and to figure out the opportunities and threats in the macro environment – technological, environmental, political, economic, social, demographic, etc in which Gene Therapeutics operates in.

According to Harvard Business Review, 75% of the managers use SWOT analysis for various purposes such as – evaluating current scenario, strategic planning, new venture feasibility, personal growth goals, new market entry, Go To market strategies, portfolio management and strategic trade-off assessment, organizational restructuring, etc.




SWOT Objectives / Importance of SWOT Analysis and SWOT Matrix


SWOT analysis of Spark Therapeutics: Pioneering Gene Therapy can be done for the following purposes –
1. Strategic planning using facts provided in Spark Therapeutics: Pioneering Gene Therapy case study
2. Improving business portfolio management of Gene Therapeutics
3. Assessing feasibility of the new initiative in Innovation & Entrepreneurship field.
4. Making a Innovation & Entrepreneurship topic specific business decision
5. Set goals for the organization
6. Organizational restructuring of Gene Therapeutics




Strengths Spark Therapeutics: Pioneering Gene Therapy | Internal Strategic Factors
What are Strengths in SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

The strengths of Gene Therapeutics in Spark Therapeutics: Pioneering Gene Therapy Harvard Business Review case study are -

Organizational Resilience of Gene Therapeutics

– The covid-19 pandemic has put organizational resilience at the centre of everthing that Gene Therapeutics does. Organizational resilience comprises - Financial Resilience, Operational Resilience, Technological Resilience, Organizational Resilience, Business Model Resilience, and Reputation Resilience.

Digital Transformation in Innovation & Entrepreneurship segment

- digital transformation varies from industry to industry. For Gene Therapeutics digital transformation journey comprises differing goals based on market maturity, customer technology acceptance, and organizational culture. Gene Therapeutics has successfully integrated the four key components of digital transformation – digital integration in processes, digital integration in marketing and customer relationship management, digital integration into the value chain, and using technology to explore new products and market opportunities.

Learning organization

- Gene Therapeutics is a learning organization. It has inculcated three key characters of learning organization in its processes and operations – exploration, creativity, and expansiveness. The work place at Gene Therapeutics is open place that encourages instructiveness, ideation, open minded discussions, and creativity. Employees and leaders in Spark Therapeutics: Pioneering Gene Therapy Harvard Business Review case study emphasize – knowledge, initiative, and innovation.

Sustainable margins compare to other players in Innovation & Entrepreneurship industry

– Spark Therapeutics: Pioneering Gene Therapy firm has clearly differentiated products in the market place. This has enabled Gene Therapeutics to fetch slight price premium compare to the competitors in the Innovation & Entrepreneurship industry. The sustainable margins have also helped Gene Therapeutics to invest into research and development (R&D) and innovation.

High brand equity

– Gene Therapeutics has strong brand awareness and brand recognition among both - the exiting customers and potential new customers. Strong brand equity has enabled Gene Therapeutics to keep acquiring new customers and building profitable relationship with both the new and loyal customers.

Successful track record of launching new products

– Gene Therapeutics has launched numerous new products in last few years, keeping in mind evolving customer preferences and competitive pressures. Gene Therapeutics has effective processes in place that helps in exploring new product needs, doing quick pilot testing, and then launching the products quickly using its extensive distribution network.

Superior customer experience

– The customer experience strategy of Gene Therapeutics in the segment is based on four key concepts – personalization, simplification of complex needs, prompt response, and continuous engagement.

Cross disciplinary teams

– Horizontal connected teams at the Gene Therapeutics are driving operational speed, building greater agility, and keeping the organization nimble to compete with new competitors. It helps are organization to ideate new ideas, and execute them swiftly in the marketplace.

Low bargaining power of suppliers

– Suppliers of Gene Therapeutics in the sector have low bargaining power. Spark Therapeutics: Pioneering Gene Therapy has further diversified its suppliers portfolio by building a robust supply chain across various countries. This helps Gene Therapeutics to manage not only supply disruptions but also source products at highly competitive prices.

Analytics focus

– Gene Therapeutics is putting a lot of focus on utilizing the power of analytics in business decision making. This has put it among the leading players in the industry. The technology infrastructure suggested by Robert F. Higgins can also help it to harness the power of analytics for – marketing optimization, demand forecasting, customer relationship management, inventory management, information sharing across the value chain etc.

Highly skilled collaborators

– Gene Therapeutics has highly efficient outsourcing and offshoring strategy. It has resulted in greater operational flexibility and bringing down the costs in highly price sensitive segment. Secondly the value chain collaborators of the firm in Spark Therapeutics: Pioneering Gene Therapy HBR case study have helped the firm to develop new products and bring them quickly to the marketplace.

Effective Research and Development (R&D)

– Gene Therapeutics has innovation driven culture where significant part of the revenues are spent on the research and development activities. This has resulted in, as mentioned in case study Spark Therapeutics: Pioneering Gene Therapy - staying ahead in the industry in terms of – new product launches, superior customer experience, highly competitive pricing strategies, and great returns to the shareholders.






Weaknesses Spark Therapeutics: Pioneering Gene Therapy | Internal Strategic Factors
What are Weaknesses in SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

The weaknesses of Spark Therapeutics: Pioneering Gene Therapy are -

Slow decision making process

– As mentioned earlier in the report, Gene Therapeutics has a very deliberative decision making approach. This approach has resulted in prudent decisions, but it has also resulted in missing opportunities in the industry over the last five years. Gene Therapeutics even though has strong showing on digital transformation primary two stages, it has struggled to capitalize the power of digital transformation in marketing efforts and new venture efforts.

Compensation and incentives

– The revenue per employee as mentioned in the HBR case study Spark Therapeutics: Pioneering Gene Therapy, is just above the industry average. Gene Therapeutics needs to redesign the compensation structure and incentives to increase the revenue per employees. Some of the steps that it can take are – hiring more specialists on project basis, etc.

Skills based hiring

– The stress on hiring functional specialists at Gene Therapeutics has created an environment where the organization is dominated by functional specialists rather than management generalist. This has resulted into product oriented approach rather than marketing oriented approach or consumers oriented approach.

High dependence on existing supply chain

– The disruption in the global supply chains because of the Covid-19 pandemic and blockage of the Suez Canal illustrated the fragile nature of Gene Therapeutics supply chain. Even after few cautionary changes mentioned in the HBR case study - Spark Therapeutics: Pioneering Gene Therapy, it is still heavily dependent upon the existing supply chain. The existing supply chain though brings in cost efficiencies but it has left Gene Therapeutics vulnerable to further global disruptions in South East Asia.

Products dominated business model

– Even though Gene Therapeutics has some of the most successful products in the industry, this business model has made each new product launch extremely critical for continuous financial growth of the organization. firm in the HBR case study - Spark Therapeutics: Pioneering Gene Therapy should strive to include more intangible value offerings along with its core products and services.

Low market penetration in new markets

– Outside its home market of Gene Therapeutics, firm in the HBR case study Spark Therapeutics: Pioneering Gene Therapy needs to spend more promotional, marketing, and advertising efforts to penetrate international markets.

Need for greater diversity

– Gene Therapeutics has taken concrete steps on diversity, equity, and inclusion. But the efforts so far has resulted in limited success. It needs to expand the recruitment and selection process to hire more people from the minorities and underprivileged background.

Lack of clear differentiation of Gene Therapeutics products

– To increase the profitability and margins on the products, Gene Therapeutics needs to provide more differentiated products than what it is currently offering in the marketplace.

High cash cycle compare to competitors

Gene Therapeutics has a high cash cycle compare to other players in the industry. It needs to shorten the cash cycle by 12% to be more competitive in the marketplace, reduce inventory costs, and be more profitable.

Increasing silos among functional specialists

– The organizational structure of Gene Therapeutics is dominated by functional specialists. It is not different from other players in the Innovation & Entrepreneurship segment. Gene Therapeutics needs to de-silo the office environment to harness the true potential of its workforce. Secondly the de-silo will also help Gene Therapeutics to focus more on services rather than just following the product oriented approach.

No frontier risks strategy

– After analyzing the HBR case study Spark Therapeutics: Pioneering Gene Therapy, it seems that company is thinking about the frontier risks that can impact Innovation & Entrepreneurship strategy. But it has very little resources allocation to manage the risks emerging from events such as natural disasters, climate change, melting of permafrost, tacking the rise of artificial intelligence, opportunities and threats emerging from commercialization of space etc.




Opportunities Spark Therapeutics: Pioneering Gene Therapy | External Strategic Factors
What are Opportunities in the SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis


The opportunities highlighted in the Harvard Business Review case study Spark Therapeutics: Pioneering Gene Therapy are -

Remote work and new talent hiring opportunities

– The widespread usage of remote working technologies during Covid-19 has opened opportunities for Gene Therapeutics to expand its talent hiring zone. According to McKinsey Global Institute, 20% of the high end workforce in fields such as finance, information technology, can continously work from remote local post Covid-19. This presents a really great opportunity for Gene Therapeutics to hire the very best people irrespective of their geographical location.

Use of Bitcoin and other crypto currencies for transactions

– The popularity of Bitcoin and other crypto currencies as asset class and medium of transaction has opened new opportunities for Gene Therapeutics in the consumer business. Now Gene Therapeutics can target international markets with far fewer capital restrictions requirements than the existing system.

Low interest rates

– Even though inflation is raising its head in most developed economies, Gene Therapeutics can still utilize the low interest rates to borrow money for capital investment. Secondly it can also use the increase of government spending in infrastructure projects to get new business.

Redefining models of collaboration and team work

– As explained in the weaknesses section, Gene Therapeutics is facing challenges because of the dominance of functional experts in the organization. Spark Therapeutics: Pioneering Gene Therapy case study suggests that firm can utilize new technology to build more coordinated teams and streamline operations and communications using tools such as CAD, Zoom, etc.

Building a culture of innovation

– managers at Gene Therapeutics can make experimentation a productive activity and build a culture of innovation using approaches such as – mining transaction data, A/B testing of websites and selling platforms, engaging potential customers over various needs, and building on small ideas in the Innovation & Entrepreneurship segment.

Learning at scale

– Online learning technologies has now opened space for Gene Therapeutics to conduct training and development for its employees across the world. This will result in not only reducing the cost of training but also help employees in different part of the world to integrate with the headquarter work culture, ethos, and standards.

Manufacturing automation

– Gene Therapeutics can use the latest technology developments to improve its manufacturing and designing process in Innovation & Entrepreneurship segment. It can use CAD and 3D printing to build a quick prototype and pilot testing products. It can leverage automation using machine learning and artificial intelligence to do faster production at lowers costs, and it can leverage the growth in satellite and tracking technologies to improve inventory management, transportation, and shipping.

Reforming the budgeting process

- By establishing new metrics that will be used to evaluate both existing and potential projects Gene Therapeutics can not only reduce the costs of the project but also help it in integrating the projects with other processes within the organization.

Increase in government spending

– As the United States and other governments are increasing social spending and infrastructure spending to build economies post Covid-19, Gene Therapeutics can use these opportunities to build new business models that can help the communities that Gene Therapeutics operates in. Secondly it can use opportunities from government spending in Innovation & Entrepreneurship sector.

Leveraging digital technologies

– Gene Therapeutics can leverage digital technologies such as artificial intelligence and machine learning to automate the production process, customer analytics to get better insights into consumer behavior, realtime digital dashboards to get better sales tracking, logistics and transportation, product tracking, etc.

Using analytics as competitive advantage

– Gene Therapeutics has spent a significant amount of money and effort to integrate analytics and machine learning into its operations in the sector. This continuous investment in analytics has enabled, as illustrated in the Harvard case study Spark Therapeutics: Pioneering Gene Therapy - to build a competitive advantage using analytics. The analytics driven competitive advantage can help Gene Therapeutics to build faster Go To Market strategies, better consumer insights, developing relevant product features, and building a highly efficient supply chain.

Harnessing reconfiguration of the global supply chains

– As the trade war between US and China heats up in the coming years, Gene Therapeutics can build a diversified supply chain model across various countries in - South East Asia, India, and other parts of the world. This reconfiguration of global supply chain can help, as suggested in case study, Spark Therapeutics: Pioneering Gene Therapy, to buy more products closer to the markets, and it can leverage its size and influence to get better deal from the local markets.

Changes in consumer behavior post Covid-19

– Consumer behavior has changed in the Innovation & Entrepreneurship industry because of Covid-19 restrictions. Some of this behavior will stay once things get back to normal. Gene Therapeutics can take advantage of these changes in consumer behavior to build a far more efficient business model. For example consumer regular ordering of products can reduce both last mile delivery costs and market penetration costs. Gene Therapeutics can further use this consumer data to build better customer loyalty, provide better products and service collection, and improve the value proposition in inflationary times.




Threats Spark Therapeutics: Pioneering Gene Therapy External Strategic Factors
What are Threats in the SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis


The threats mentioned in the HBR case study Spark Therapeutics: Pioneering Gene Therapy are -

New competition

– After the dotcom bust of 2001, financial crisis of 2008-09, the business formation in US economy had declined. But in 2020 alone, there are more than 1.5 million new business applications in United States. This can lead to greater competition for Gene Therapeutics in the Innovation & Entrepreneurship sector and impact the bottomline of the organization.

Regulatory challenges

– Gene Therapeutics needs to prepare for regulatory challenges as consumer protection groups and other pressure groups are vigorously advocating for more regulations on big business - to reduce inequality, to create a level playing field, to product data privacy and consumer privacy, to reduce the influence of big money on democratic institutions, etc. This can lead to significant changes in the Innovation & Entrepreneurship industry regulations.

High dependence on third party suppliers

– Gene Therapeutics high dependence on third party suppliers can disrupt its processes and delivery mechanism. For example -the current troubles of car makers because of chip shortage is because the chip companies started producing chips for electronic companies rather than car manufacturers.

Environmental challenges

– Gene Therapeutics needs to have a robust strategy against the disruptions arising from climate change and energy requirements. EU has identified it as key priority area and spending 30% of its 880 billion Euros European post Covid-19 recovery funds on green technology. Gene Therapeutics can take advantage of this fund but it will also bring new competitors in the Innovation & Entrepreneurship industry.

Trade war between China and United States

– The trade war between two of the biggest economies can hugely impact the opportunities for Gene Therapeutics in the Innovation & Entrepreneurship industry. The Innovation & Entrepreneurship industry is already at various protected from local competition in China, with the rise of trade war the protection levels may go up. This presents a clear threat of current business model in Chinese market.

Stagnating economy with rate increase

– Gene Therapeutics can face lack of demand in the market place because of Fed actions to reduce inflation. This can lead to sluggish growth in the economy, lower demands, lower investments, higher borrowing costs, and consolidation in the field.

Aging population

– As the populations of most advanced economies are aging, it will lead to high social security costs, higher savings among population, and lower demand for goods and services in the economy. The household savings in US, France, UK, Germany, and Japan are growing faster than predicted because of uncertainty caused by pandemic.

Increasing international competition and downward pressure on margins

– Apart from technology driven competitive advantage dilution, Gene Therapeutics can face downward pressure on margins from increasing competition from international players. The international players have stable revenue in their home market and can use those resources to penetrate prominent markets illustrated in HBR case study Spark Therapeutics: Pioneering Gene Therapy .

Capital market disruption

– During the Covid-19, Dow Jones has touched record high. The valuations of a number of companies are way beyond their existing business model potential. This can lead to capital market correction which can put a number of suppliers, collaborators, value chain partners in great financial difficulty. It will directly impact the business of Gene Therapeutics.

Barriers of entry lowering

– As technology is more democratized, the barriers to entry in the industry are lowering. It can presents Gene Therapeutics with greater competitive threats in the near to medium future. Secondly it will also put downward pressure on pricing throughout the sector.

Technology disruption because of hacks, piracy etc

– The colonial pipeline illustrated, how vulnerable modern organization are to international hackers, miscreants, and disruptors. The cyber security interruption, data leaks, etc can seriously jeopardize the future growth of the organization.

Technology acceleration in Forth Industrial Revolution

– Gene Therapeutics has witnessed rapid integration of technology during Covid-19 in the Innovation & Entrepreneurship industry. As one of the leading players in the industry, Gene Therapeutics needs to keep up with the evolution of technology in the Innovation & Entrepreneurship sector. According to Mckinsey study top managers believe that the adoption of technology in operations, communications is 20-25 times faster than what they planned in the beginning of 2019.

Consumer confidence and its impact on Gene Therapeutics demand

– There is a high probability of declining consumer confidence, given – high inflammation rate, rise of gig economy, lower job stability, increasing cost of living, higher interest rates, and aging demography. All the factors contribute to people saving higher rate of their income, resulting in lower consumer demand in the industry and other sectors.




Weighted SWOT Analysis of Spark Therapeutics: Pioneering Gene Therapy Template, Example


Not all factors mentioned under the Strengths, Weakness, Opportunities, and Threats quadrants in the SWOT Analysis are equal. Managers in the HBR case study Spark Therapeutics: Pioneering Gene Therapy needs to zero down on the relative importance of each factor mentioned in the Strengths, Weakness, Opportunities, and Threats quadrants. We can provide the relative importance to each factor by assigning relative weights. Weighted SWOT analysis process is a three stage process –

First stage for doing weighted SWOT analysis of the case study Spark Therapeutics: Pioneering Gene Therapy is to rank the strengths and weaknesses of the organization. This will help you to assess the most important strengths and weaknesses of the firm and which one of the strengths and weaknesses mentioned in the initial lists are marginal and can be left out.

Second stage for conducting weighted SWOT analysis of the Harvard case study Spark Therapeutics: Pioneering Gene Therapy is to give probabilities to the external strategic factors thus better understanding the opportunities and threats arising out of macro environment changes and developments.

Third stage of constructing weighted SWOT analysis of Spark Therapeutics: Pioneering Gene Therapy is to provide strategic recommendations includes – joining likelihood of external strategic factors such as opportunities and threats to the internal strategic factors – strengths and weaknesses. You should start with external factors as they will provide the direction of the overall industry. Secondly by joining probabilities with internal strategic factors can help the company not only strategic fit but also the most probably strategic trade-off that Gene Therapeutics needs to make to build a sustainable competitive advantage.



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