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The CRISPR-Cas9 Quarrel SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

Case Study SWOT Analysis Solution

Case Study Description of The CRISPR-Cas9 Quarrel


In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to cure previously incurable genetic diseases such as sickle cell anemia and cystic fibrosis, among many others. The dispute had escalated to the point where the U.S. Patent and Trademark Office (USPTO) declared a patent interference and began a process to determine the intellectual property's (IP) rightful owner. The USPTO's decision would not only have serious commercial implications-the technology would be immensely important to biotechnology firms looking to develop gene therapy products, and was therefore sure to generate strong revenues for whichever entity owned the IP-but would also essentially award scientific credit for this technology and thus impact the reputations of the scientists on both sides who had worked so hard to discover the tool. This case touches upon a number of other key issues too: the ethical implications of gene editing; the state of IP and licensing in the biotechnology industry; the impact of lawsuits on developing new technologies and companies; and who should own platform technologies built, at least in part, by the research of multiple parties and government funding.

Authors :: Richard G. Hamermesh, Matthew Preble

Topics :: Innovation & Entrepreneurship

Tags :: Intellectual property, Strategy, SWOT Analysis, SWOT Matrix, TOWS, Weighted SWOT Analysis

Swot Analysis of "The CRISPR-Cas9 Quarrel" written by Richard G. Hamermesh, Matthew Preble includes – strengths weakness that are internal strategic factors of the organization, and opportunities and threats that Cas9 Crispr facing as an external strategic factors. Some of the topics covered in The CRISPR-Cas9 Quarrel case study are - Strategic Management Strategies, Intellectual property, Strategy and Innovation & Entrepreneurship.


Some of the macro environment factors that can be used to understand the The CRISPR-Cas9 Quarrel casestudy better are - – talent flight as more people leaving formal jobs, geopolitical disruptions, challanges to central banks by blockchain based private currencies, competitive advantages are harder to sustain because of technology dispersion, supply chains are disrupted by pandemic , there is backlash against globalization, increasing government debt because of Covid-19 spendings, there is increasing trade war between United States & China, increasing commodity prices, etc



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Introduction to SWOT Analysis of The CRISPR-Cas9 Quarrel


SWOT stands for an organization’s Strengths, Weaknesses, Opportunities and Threats . At Oak Spring University , we believe that protagonist in The CRISPR-Cas9 Quarrel case study can use SWOT analysis as a strategic management tool to assess the current internal strengths and weaknesses of the Cas9 Crispr, and to figure out the opportunities and threats in the macro environment – technological, environmental, political, economic, social, demographic, etc in which Cas9 Crispr operates in.

According to Harvard Business Review, 75% of the managers use SWOT analysis for various purposes such as – evaluating current scenario, strategic planning, new venture feasibility, personal growth goals, new market entry, Go To market strategies, portfolio management and strategic trade-off assessment, organizational restructuring, etc.




SWOT Objectives / Importance of SWOT Analysis and SWOT Matrix


SWOT analysis of The CRISPR-Cas9 Quarrel can be done for the following purposes –
1. Strategic planning using facts provided in The CRISPR-Cas9 Quarrel case study
2. Improving business portfolio management of Cas9 Crispr
3. Assessing feasibility of the new initiative in Innovation & Entrepreneurship field.
4. Making a Innovation & Entrepreneurship topic specific business decision
5. Set goals for the organization
6. Organizational restructuring of Cas9 Crispr




Strengths The CRISPR-Cas9 Quarrel | Internal Strategic Factors
What are Strengths in SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

The strengths of Cas9 Crispr in The CRISPR-Cas9 Quarrel Harvard Business Review case study are -

Effective Research and Development (R&D)

– Cas9 Crispr has innovation driven culture where significant part of the revenues are spent on the research and development activities. This has resulted in, as mentioned in case study The CRISPR-Cas9 Quarrel - staying ahead in the industry in terms of – new product launches, superior customer experience, highly competitive pricing strategies, and great returns to the shareholders.

Superior customer experience

– The customer experience strategy of Cas9 Crispr in the segment is based on four key concepts – personalization, simplification of complex needs, prompt response, and continuous engagement.

Organizational Resilience of Cas9 Crispr

– The covid-19 pandemic has put organizational resilience at the centre of everthing that Cas9 Crispr does. Organizational resilience comprises - Financial Resilience, Operational Resilience, Technological Resilience, Organizational Resilience, Business Model Resilience, and Reputation Resilience.

Ability to recruit top talent

– Cas9 Crispr is one of the leading recruiters in the industry. Managers in the The CRISPR-Cas9 Quarrel are in a position to attract the best talent available. The firm has a robust talent identification program that helps in identifying the brightest.

Highly skilled collaborators

– Cas9 Crispr has highly efficient outsourcing and offshoring strategy. It has resulted in greater operational flexibility and bringing down the costs in highly price sensitive segment. Secondly the value chain collaborators of the firm in The CRISPR-Cas9 Quarrel HBR case study have helped the firm to develop new products and bring them quickly to the marketplace.

Training and development

– Cas9 Crispr has one of the best training and development program in the industry. The effectiveness of the training programs can be measured in The CRISPR-Cas9 Quarrel Harvard Business Review case study by analyzing – employees retention, in-house promotion, loyalty, new venture initiation, lack of conflict, and high level of both employees and customer engagement.

Operational resilience

– The operational resilience strategy in the The CRISPR-Cas9 Quarrel Harvard Business Review case study comprises – understanding the underlying the factors in the industry, building diversified operations across different geographies so that disruption in one part of the world doesn’t impact the overall performance of the firm, and integrating the various business operations and processes through its digital transformation drive.

Successful track record of launching new products

– Cas9 Crispr has launched numerous new products in last few years, keeping in mind evolving customer preferences and competitive pressures. Cas9 Crispr has effective processes in place that helps in exploring new product needs, doing quick pilot testing, and then launching the products quickly using its extensive distribution network.

High brand equity

– Cas9 Crispr has strong brand awareness and brand recognition among both - the exiting customers and potential new customers. Strong brand equity has enabled Cas9 Crispr to keep acquiring new customers and building profitable relationship with both the new and loyal customers.

Ability to lead change in Innovation & Entrepreneurship field

– Cas9 Crispr is one of the leading players in its industry. Over the years it has not only transformed the business landscape in its segment but also across the whole industry. The ability to lead change has enabled Cas9 Crispr in – penetrating new markets, reaching out to new customers, and providing different value propositions to different customers in the international markets.

Innovation driven organization

– Cas9 Crispr is one of the most innovative firm in sector. Manager in The CRISPR-Cas9 Quarrel Harvard Business Review case study can use Clayton Christensen Disruptive Innovation strategies to further increase the scale of innovtions in the organization.

Diverse revenue streams

– Cas9 Crispr is present in almost all the verticals within the industry. This has provided firm in The CRISPR-Cas9 Quarrel case study a diverse revenue stream that has helped it to survive disruptions such as global pandemic in Covid-19, financial disruption of 2008, and supply chain disruption of 2021.






Weaknesses The CRISPR-Cas9 Quarrel | Internal Strategic Factors
What are Weaknesses in SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis

The weaknesses of The CRISPR-Cas9 Quarrel are -

High bargaining power of channel partners

– Because of the regulatory requirements, Richard G. Hamermesh, Matthew Preble suggests that, Cas9 Crispr is facing high bargaining power of the channel partners. So far it has not able to streamline the operations to reduce the bargaining power of the value chain partners in the industry.

Aligning sales with marketing

– It come across in the case study The CRISPR-Cas9 Quarrel that the firm needs to have more collaboration between its sales team and marketing team. Sales professionals in the industry have deep experience in developing customer relationships. Marketing department in the case The CRISPR-Cas9 Quarrel can leverage the sales team experience to cultivate customer relationships as Cas9 Crispr is planning to shift buying processes online.

Slow decision making process

– As mentioned earlier in the report, Cas9 Crispr has a very deliberative decision making approach. This approach has resulted in prudent decisions, but it has also resulted in missing opportunities in the industry over the last five years. Cas9 Crispr even though has strong showing on digital transformation primary two stages, it has struggled to capitalize the power of digital transformation in marketing efforts and new venture efforts.

Low market penetration in new markets

– Outside its home market of Cas9 Crispr, firm in the HBR case study The CRISPR-Cas9 Quarrel needs to spend more promotional, marketing, and advertising efforts to penetrate international markets.

Compensation and incentives

– The revenue per employee as mentioned in the HBR case study The CRISPR-Cas9 Quarrel, is just above the industry average. Cas9 Crispr needs to redesign the compensation structure and incentives to increase the revenue per employees. Some of the steps that it can take are – hiring more specialists on project basis, etc.

Slow to harness new channels of communication

– Even though competitors are using new communication channels such as Instagram, Tiktok, and Snap, Cas9 Crispr is slow explore the new channels of communication. These new channels of communication mentioned in marketing section of case study The CRISPR-Cas9 Quarrel can help to provide better information regarding products and services. It can also build an online community to further reach out to potential customers.

Increasing silos among functional specialists

– The organizational structure of Cas9 Crispr is dominated by functional specialists. It is not different from other players in the Innovation & Entrepreneurship segment. Cas9 Crispr needs to de-silo the office environment to harness the true potential of its workforce. Secondly the de-silo will also help Cas9 Crispr to focus more on services rather than just following the product oriented approach.

Lack of clear differentiation of Cas9 Crispr products

– To increase the profitability and margins on the products, Cas9 Crispr needs to provide more differentiated products than what it is currently offering in the marketplace.

Need for greater diversity

– Cas9 Crispr has taken concrete steps on diversity, equity, and inclusion. But the efforts so far has resulted in limited success. It needs to expand the recruitment and selection process to hire more people from the minorities and underprivileged background.

High dependence on existing supply chain

– The disruption in the global supply chains because of the Covid-19 pandemic and blockage of the Suez Canal illustrated the fragile nature of Cas9 Crispr supply chain. Even after few cautionary changes mentioned in the HBR case study - The CRISPR-Cas9 Quarrel, it is still heavily dependent upon the existing supply chain. The existing supply chain though brings in cost efficiencies but it has left Cas9 Crispr vulnerable to further global disruptions in South East Asia.

Products dominated business model

– Even though Cas9 Crispr has some of the most successful products in the industry, this business model has made each new product launch extremely critical for continuous financial growth of the organization. firm in the HBR case study - The CRISPR-Cas9 Quarrel should strive to include more intangible value offerings along with its core products and services.




Opportunities The CRISPR-Cas9 Quarrel | External Strategic Factors
What are Opportunities in the SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis


The opportunities highlighted in the Harvard Business Review case study The CRISPR-Cas9 Quarrel are -

Redefining models of collaboration and team work

– As explained in the weaknesses section, Cas9 Crispr is facing challenges because of the dominance of functional experts in the organization. The CRISPR-Cas9 Quarrel case study suggests that firm can utilize new technology to build more coordinated teams and streamline operations and communications using tools such as CAD, Zoom, etc.

Harnessing reconfiguration of the global supply chains

– As the trade war between US and China heats up in the coming years, Cas9 Crispr can build a diversified supply chain model across various countries in - South East Asia, India, and other parts of the world. This reconfiguration of global supply chain can help, as suggested in case study, The CRISPR-Cas9 Quarrel, to buy more products closer to the markets, and it can leverage its size and influence to get better deal from the local markets.

Increase in government spending

– As the United States and other governments are increasing social spending and infrastructure spending to build economies post Covid-19, Cas9 Crispr can use these opportunities to build new business models that can help the communities that Cas9 Crispr operates in. Secondly it can use opportunities from government spending in Innovation & Entrepreneurship sector.

Developing new processes and practices

– Cas9 Crispr can develop new processes and procedures in Innovation & Entrepreneurship industry using technology such as automation using artificial intelligence, real time transportation and products tracking, 3D modeling for concept development and new products pilot testing etc.

Identify volunteer opportunities

– Covid-19 has impacted working population in two ways – it has led to people soul searching about their professional choices, resulting in mass resignation. Secondly it has encouraged people to do things that they are passionate about. This has opened opportunities for businesses to build volunteer oriented socially driven projects. Cas9 Crispr can explore opportunities that can attract volunteers and are consistent with its mission and vision.

Finding new ways to collaborate

– Covid-19 has not only transformed business models of companies in Innovation & Entrepreneurship industry, but it has also influenced the consumer preferences. Cas9 Crispr can tie-up with other value chain partners to explore new opportunities regarding meeting customer demands and building a rewarding and engaging relationship.

Changes in consumer behavior post Covid-19

– Consumer behavior has changed in the Innovation & Entrepreneurship industry because of Covid-19 restrictions. Some of this behavior will stay once things get back to normal. Cas9 Crispr can take advantage of these changes in consumer behavior to build a far more efficient business model. For example consumer regular ordering of products can reduce both last mile delivery costs and market penetration costs. Cas9 Crispr can further use this consumer data to build better customer loyalty, provide better products and service collection, and improve the value proposition in inflationary times.

Better consumer reach

– The expansion of the 5G network will help Cas9 Crispr to increase its market reach. Cas9 Crispr will be able to reach out to new customers. Secondly 5G will also provide technology framework to build new tools and products that can help more immersive consumer experience and faster consumer journey.

Reconfiguring business model

– The expansion of digital payment system, the bringing down of international transactions costs using Bitcoin and other blockchain based currencies, etc can help Cas9 Crispr to reconfigure its entire business model. For example it can used blockchain based technologies to reduce piracy of its products in the big markets such as China. Secondly it can use the popularity of e-commerce in various developing markets to build a Direct to Customer business model rather than the current Channel Heavy distribution network.

Building a culture of innovation

– managers at Cas9 Crispr can make experimentation a productive activity and build a culture of innovation using approaches such as – mining transaction data, A/B testing of websites and selling platforms, engaging potential customers over various needs, and building on small ideas in the Innovation & Entrepreneurship segment.

Learning at scale

– Online learning technologies has now opened space for Cas9 Crispr to conduct training and development for its employees across the world. This will result in not only reducing the cost of training but also help employees in different part of the world to integrate with the headquarter work culture, ethos, and standards.

Buying journey improvements

– Cas9 Crispr can improve the customer journey of consumers in the industry by using analytics and artificial intelligence. The CRISPR-Cas9 Quarrel suggest that firm can provide automated chats to help consumers solve their own problems, provide online suggestions to get maximum out of the products and services, and help consumers to build a community where they can interact with each other to develop new features and uses.

Reforming the budgeting process

- By establishing new metrics that will be used to evaluate both existing and potential projects Cas9 Crispr can not only reduce the costs of the project but also help it in integrating the projects with other processes within the organization.




Threats The CRISPR-Cas9 Quarrel External Strategic Factors
What are Threats in the SWOT Analysis / TOWS Matrix / Weighted SWOT Analysis


The threats mentioned in the HBR case study The CRISPR-Cas9 Quarrel are -

Increasing international competition and downward pressure on margins

– Apart from technology driven competitive advantage dilution, Cas9 Crispr can face downward pressure on margins from increasing competition from international players. The international players have stable revenue in their home market and can use those resources to penetrate prominent markets illustrated in HBR case study The CRISPR-Cas9 Quarrel .

Stagnating economy with rate increase

– Cas9 Crispr can face lack of demand in the market place because of Fed actions to reduce inflation. This can lead to sluggish growth in the economy, lower demands, lower investments, higher borrowing costs, and consolidation in the field.

Capital market disruption

– During the Covid-19, Dow Jones has touched record high. The valuations of a number of companies are way beyond their existing business model potential. This can lead to capital market correction which can put a number of suppliers, collaborators, value chain partners in great financial difficulty. It will directly impact the business of Cas9 Crispr.

Trade war between China and United States

– The trade war between two of the biggest economies can hugely impact the opportunities for Cas9 Crispr in the Innovation & Entrepreneurship industry. The Innovation & Entrepreneurship industry is already at various protected from local competition in China, with the rise of trade war the protection levels may go up. This presents a clear threat of current business model in Chinese market.

Learning curve for new practices

– As the technology based on artificial intelligence and machine learning platform is getting complex, as highlighted in case study The CRISPR-Cas9 Quarrel, Cas9 Crispr may face longer learning curve for training and development of existing employees. This can open space for more nimble competitors in the field of Innovation & Entrepreneurship .

Technology acceleration in Forth Industrial Revolution

– Cas9 Crispr has witnessed rapid integration of technology during Covid-19 in the Innovation & Entrepreneurship industry. As one of the leading players in the industry, Cas9 Crispr needs to keep up with the evolution of technology in the Innovation & Entrepreneurship sector. According to Mckinsey study top managers believe that the adoption of technology in operations, communications is 20-25 times faster than what they planned in the beginning of 2019.

Shortening product life cycle

– it is one of the major threat that Cas9 Crispr is facing in Innovation & Entrepreneurship sector. It can lead to higher research and development costs, higher marketing expenses, lower customer loyalty, etc.

Backlash against dominant players

– US Congress and other legislative arms of the government are getting tough on big business especially technology companies. The digital arm of Cas9 Crispr business can come under increasing regulations regarding data privacy, data security, etc.

New competition

– After the dotcom bust of 2001, financial crisis of 2008-09, the business formation in US economy had declined. But in 2020 alone, there are more than 1.5 million new business applications in United States. This can lead to greater competition for Cas9 Crispr in the Innovation & Entrepreneurship sector and impact the bottomline of the organization.

Consumer confidence and its impact on Cas9 Crispr demand

– There is a high probability of declining consumer confidence, given – high inflammation rate, rise of gig economy, lower job stability, increasing cost of living, higher interest rates, and aging demography. All the factors contribute to people saving higher rate of their income, resulting in lower consumer demand in the industry and other sectors.

Technology disruption because of hacks, piracy etc

– The colonial pipeline illustrated, how vulnerable modern organization are to international hackers, miscreants, and disruptors. The cyber security interruption, data leaks, etc can seriously jeopardize the future growth of the organization.

Regulatory challenges

– Cas9 Crispr needs to prepare for regulatory challenges as consumer protection groups and other pressure groups are vigorously advocating for more regulations on big business - to reduce inequality, to create a level playing field, to product data privacy and consumer privacy, to reduce the influence of big money on democratic institutions, etc. This can lead to significant changes in the Innovation & Entrepreneurship industry regulations.

High level of anxiety and lack of motivation

– the Great Resignation in United States is the sign of broader dissatisfaction among the workforce in United States. Cas9 Crispr needs to understand the core reasons impacting the Innovation & Entrepreneurship industry. This will help it in building a better workplace.




Weighted SWOT Analysis of The CRISPR-Cas9 Quarrel Template, Example


Not all factors mentioned under the Strengths, Weakness, Opportunities, and Threats quadrants in the SWOT Analysis are equal. Managers in the HBR case study The CRISPR-Cas9 Quarrel needs to zero down on the relative importance of each factor mentioned in the Strengths, Weakness, Opportunities, and Threats quadrants. We can provide the relative importance to each factor by assigning relative weights. Weighted SWOT analysis process is a three stage process –

First stage for doing weighted SWOT analysis of the case study The CRISPR-Cas9 Quarrel is to rank the strengths and weaknesses of the organization. This will help you to assess the most important strengths and weaknesses of the firm and which one of the strengths and weaknesses mentioned in the initial lists are marginal and can be left out.

Second stage for conducting weighted SWOT analysis of the Harvard case study The CRISPR-Cas9 Quarrel is to give probabilities to the external strategic factors thus better understanding the opportunities and threats arising out of macro environment changes and developments.

Third stage of constructing weighted SWOT analysis of The CRISPR-Cas9 Quarrel is to provide strategic recommendations includes – joining likelihood of external strategic factors such as opportunities and threats to the internal strategic factors – strengths and weaknesses. You should start with external factors as they will provide the direction of the overall industry. Secondly by joining probabilities with internal strategic factors can help the company not only strategic fit but also the most probably strategic trade-off that Cas9 Crispr needs to make to build a sustainable competitive advantage.



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