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PluroGen Therapeutics Net Present Value (NPV) / MBA Resources

Introduction to Net Present Value (NPV) - What is Net Present Value (NPV) ? How it impacts financial decisions regarding project management?

NPV solution for PluroGen Therapeutics case study


At Oak Spring University, we provide corporate level professional Net Present Value (NPV) case study solution. PluroGen Therapeutics case study is a Harvard Business School (HBR) case study written by Susan Chaplinsky. The PluroGen Therapeutics (referred as “Plurogen Tag” from here on) case study provides evaluation & decision scenario in field of Strategy & Execution. It also touches upon business topics such as - Value proposition, .

The net present value (NPV) of an investment proposal is the present value of the proposal’s net cash flows less the proposal’s initial cash outflow. If a project’s NPV is greater than or equal to zero, the project should be accepted.

NPV = Present Value of Future Cash Flows LESS Project’s Initial Investment






Case Description of PluroGen Therapeutics Case Study


Founded in February 2003, PluroGen Therapeutics is a start-up pharmaceutical firm that is in the process of developing a topical antimicrobial gel (TAG) to prevent and treat burn and skin-ulcer infections. In contrast to most new pharmaceutical compounds that have no clinical history, TAG has been used by thousands of patients at a large university hospital over the past 10 years. Based on the favorable clinical response, the two founding doctors want to start a company and make the drug available to the greater medical community. Although the doctors are recognized authorities in the field of wound care and holders of several patents, neither has extensive business experience. PluroGen is currently seeking $1.5 million in financing from angel investors to initiate the drug-approval process and subsequently plans to seek $6.5 million in funding from a strategic partner to complete Phase III trials and gain final approval from the U.S. Food and Drug Administration. Students are asked to evaluate whether TAG is attractive enough to be of interest to experienced investors and, if so, what percentage of equity investors would demand in return for the $1.5 million. Because of the presumed future funding by a strategic partner, the angel investors must carefully weigh the effects of the next round of financing on the terms they are demanding now.


Case Authors : Susan Chaplinsky

Topic : Strategy & Execution

Related Areas :




Calculating Net Present Value (NPV) at 6% for PluroGen Therapeutics Case Study


Years              Cash Flow     Net Cash Flow     Cumulative    
Cash Flow
Discount Rate
@ 6 %
Discounted
Cash Flows
Year 0 (10028599) -10028599 - -
Year 1 3446880 -6581719 3446880 0.9434 3251774
Year 2 3980791 -2600928 7427671 0.89 3542890
Year 3 3968683 1367755 11396354 0.8396 3332183
Year 4 3244131 4611886 14640485 0.7921 2569656
TOTAL 14640485 12696502




The Net Present Value at 6% discount rate is 2667903

In isolation the NPV number doesn't mean much but put in right context then it is one of the best method to evaluate project returns. In this article we will cover -

Different methods of capital budgeting


What is NPV & Formula of NPV,
How it is calculated,
How to use NPV number for project evaluation, and
Scenario Planning given risks and management priorities.




Capital Budgeting Approaches

Methods of Capital Budgeting


There are four types of capital budgeting techniques that are widely used in the corporate world –

1. Payback Period
2. Net Present Value
3. Internal Rate of Return
4. Profitability Index

Apart from the Payback period method which is an additive method, rest of the methods are based on Discounted Cash Flow technique. Even though cash flow can be calculated based on the nature of the project, for the simplicity of the article we are assuming that all the expected cash flows are realized at the end of the year.

Discounted Cash Flow approaches provide a more objective basis for evaluating and selecting investment projects. They take into consideration both –

1. Magnitude of both incoming and outgoing cash flows – Projects can be capital intensive, time intensive, or both. Plurogen Tag shareholders have preference for diversified projects investment rather than prospective high income from a single capital intensive project.
2. Timing of the expected cash flows – stockholders of Plurogen Tag have higher preference for cash returns over 4-5 years rather than 10-15 years given the nature of the volatility in the industry.






Formula and Steps to Calculate Net Present Value (NPV) of PluroGen Therapeutics

NPV = Net Cash In Flowt1 / (1+r)t1 + Net Cash In Flowt2 / (1+r)t2 + … Net Cash In Flowtn / (1+r)tn
Less Net Cash Out Flowt0 / (1+r)t0

Where t = time period, in this case year 1, year 2 and so on.
r = discount rate or return that could be earned using other safe proposition such as fixed deposit or treasury bond rate. Net Cash In Flow – What the firm will get each year.
Net Cash Out Flow – What the firm needs to invest initially in the project.

Step 1 – Understand the nature of the project and calculate cash flow for each year.
Step 2 – Discount those cash flow based on the discount rate.
Step 3 – Add all the discounted cash flow.
Step 4 – Selection of the project

Why Strategy & Execution Managers need to know Financial Tools such as Net Present Value (NPV)?

In our daily workplace we often come across people and colleagues who are just focused on their core competency and targets they have to deliver. For example marketing managers at Plurogen Tag often design programs whose objective is to drive brand awareness and customer reach. But how that 30 point increase in brand awareness or 10 point increase in customer touch points will result into shareholders’ value is not specified.

To overcome such scenarios managers at Plurogen Tag needs to not only know the financial aspect of project management but also needs to have tools to integrate them into part of the project development and monitoring plan.

Calculating Net Present Value (NPV) at 15%

After working through various assumptions we reached a conclusion that risk is far higher than 6%. In a reasonably stable industry with weak competition - 15% discount rate can be a good benchmark.



Years              Cash Flow     Net Cash Flow     Cumulative    
Cash Flow
Discount Rate
@ 15 %
Discounted
Cash Flows
Year 0 (10028599) -10028599 - -
Year 1 3446880 -6581719 3446880 0.8696 2997287
Year 2 3980791 -2600928 7427671 0.7561 3010050
Year 3 3968683 1367755 11396354 0.6575 2609473
Year 4 3244131 4611886 14640485 0.5718 1854842
TOTAL 10471653


The Net NPV after 4 years is 443054

(10471653 - 10028599 )








Calculating Net Present Value (NPV) at 20%


If the risk component is high in the industry then we should go for a higher hurdle rate / discount rate of 20%.

Years              Cash Flow     Net Cash Flow     Cumulative    
Cash Flow
Discount Rate
@ 20 %
Discounted
Cash Flows
Year 0 (10028599) -10028599 - -
Year 1 3446880 -6581719 3446880 0.8333 2872400
Year 2 3980791 -2600928 7427671 0.6944 2764438
Year 3 3968683 1367755 11396354 0.5787 2296692
Year 4 3244131 4611886 14640485 0.4823 1564492
TOTAL 9498022


The Net NPV after 4 years is -530577

At 20% discount rate the NPV is negative (9498022 - 10028599 ) so ideally we can't select the project if macro and micro factors don't allow financial managers of Plurogen Tag to discount cash flow at lower discount rates such as 15%.





Acceptance Criteria of a Project based on NPV

Simplest Approach – If the investment project of Plurogen Tag has a NPV value higher than Zero then finance managers at Plurogen Tag can ACCEPT the project, otherwise they can reject the project. This means that project will deliver higher returns over the period of time than any alternate investment strategy.

In theory if the required rate of return or discount rate is chosen correctly by finance managers at Plurogen Tag, then the stock price of the Plurogen Tag should change by same amount of the NPV. In real world we know that share price also reflects various other factors that can be related to both macro and micro environment.

In the same vein – accepting the project with zero NPV should result in stagnant share price. Finance managers use discount rates as a measure of risk components in the project execution process.

Sensitivity Analysis

Project selection is often a far more complex decision than just choosing it based on the NPV number. Finance managers at Plurogen Tag should conduct a sensitivity analysis to better understand not only the inherent risk of the projects but also how those risks can be either factored in or mitigated during the project execution. Sensitivity analysis helps in –

What are the uncertainties surrounding the project Initial Cash Outlay (ICO’s). ICO’s often have several different components such as land, machinery, building, and other equipment.

Understanding of risks involved in the project.

What are the key aspects of the projects that need to be monitored, refined, and retuned for continuous delivery of projected cash flows.

What can impact the cash flow of the project.

What will be a multi year spillover effect of various taxation regulations.

Some of the assumptions while using the Discounted Cash Flow Methods –

Projects are assumed to be Mutually Exclusive – This is seldom the came in modern day giant organizations where projects are often inter-related and rejecting a project solely based on NPV can result in sunk cost from a related project.

Independent projects have independent cash flows – As explained in the marketing project – though the project may look independent but in reality it is not as the brand awareness project can be closely associated with the spending on sales promotions and product specific advertising.






Negotiation Strategy of PluroGen Therapeutics

References & Further Readings

Susan Chaplinsky (2018), "PluroGen Therapeutics Harvard Business Review Case Study. Published by HBR Publications.


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